I have an S2 driver. I played with it a little at the range just to play with it, but honestly it is still setup as neutral. The more I play it the less I like the driver however, I think it's mostly the shaft because Im having issues with a slight ballooning and shots fading off right with it. I bought it while my shoulder was hurt and I think going with the regular flex shaft as recommended by GG at the time was a mistake because I've hit several stiff shafted drivers this year and they've all gone dead straight and slightly further for me.
Absolutely changed it up a bit. Got fit for a stiff 63g Diamana Blueboard shaft playing to 44.5 in my R11. I got one for a good price here on the site. Also have head ASP set to open with 10g in the toe and 4g in the heel.
My R11 15.5 FW is set to 1* higher and closed w/ stiff stock Blur.
I was messing around with different setting on my R11 driver this evening. I had been playing it .5* higher with the face on open. After reading TC's fitting thread today, I decided to change things up a little. I now have it set on "lower" with the ASP closed and seem to be getting better ball flight. I was hitting the ball straight and a nice, mid trajectory shot. I wasn't on a monitor, but I think the spin probably came down. The sound also changed coming off of the club face.
I've tinkered with both my driver and 3w. Same shaft in both (Motore F1 x), but I have them both at different settings, for some reason.
Don't think I'm quite done tinkering with my driver yet. Got my 3w set to between neutral and left, and got my driver set up between neutral and right! Something isn't quite grooving with my swing between the clubs just yet!